A case of hemophagocytic lymphohistiocytosis caused by an Epstein-Barr virus infection, presenting with unremitting fever and rash
Pediatric Emergency Medicine Journal
;
: 26-30, 2019.
Artículo
en Coreano
| WPRIM
| ID: wpr-760849
ABSTRACT
Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome caused by excessive activation of lymphocytes and macrophages, leading to cytokine storm. Infection-associated HLH is most common, and Epstein-Barr virus is the leading triggers. Quick diagnosis is essential for starting the treatment before irreversible damage. We report a case of 16-year-old boy who presented with unremitted fever, jaundice, and erythematous maculopapular rash all over the body. Investigations showed thrombocytopenia, hyperferritinemia, hypertriglycemia, and the bone marrow biopsy showed hemophagocytosis. Epstein-Barr virus antibody was positive. He responded to chemotherapy as per the HLH-2004 protocol and supportive treatment, and was discharged without complication on day 17.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Trombocitopenia
/
Biopsia
/
Médula Ósea
/
Linfocitos
/
Herpesvirus Humano 4
/
Infecciones por Virus de Epstein-Barr
/
Diagnóstico
/
Quimioterapia
/
Linfohistiocitosis Hemofagocítica
/
Exantema
Tipo de estudio:
Estudio diagnóstico
/
Guía de Práctica Clínica
Límite:
Adolescente
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Pediatric Emergency Medicine Journal
Año:
2019
Tipo del documento:
Artículo
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