Angiotensin II type 1 receptor antibodies in kidney transplantation / 대한이식학회지
The Journal of the Korean Society for Transplantation
;
: 6-12, 2019.
Artículo
en Inglés
| WPRIM
| ID: wpr-761495
ABSTRACT
Angiotensin II type 1 receptor (AT1R) antibodies directly injure endothelial and vascular smooth muscle cells by activating transcription factors associated with proinflammatory responses. Previous studies have shown that AT1R antibodies are associated with allograft rejection and decreased graft survival in kidney transplantation. Development of enzyme-linked immunosorbent assay has facilitated semiquantitative detection of AT1R antibodies. Assessing AT1R antibodies along with donor specific human leukocyte antigen antibodies may have potential to identify patients with possible risk for allograft injury and improve overall outcomes. In this review, we summarize recent clinical studies about AT1R antibodies in kidney transplantation and provide perspectives for future research area.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Donantes de Tejidos
/
Trasplante
/
Angiotensina II
/
Angiotensinas
/
Ensayo de Inmunoadsorción Enzimática
/
Trasplante de Riñón
/
Receptor de Angiotensina Tipo 1
/
Factores de Transcripción Activadores
/
Aloinjertos
/
Supervivencia de Injerto
Tipo de estudio:
Estudio pronóstico
Límite:
Humanos
Idioma:
Inglés
Revista:
The Journal of the Korean Society for Transplantation
Año:
2019
Tipo del documento:
Artículo
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