Syringocystadenocarcinoma Papilliferum: A Case Report and Review of the Literature
Annals of Dermatology
;
: 559-562, 2019.
Artículo
en Inglés
| WPRIM
| ID: wpr-762372
ABSTRACT
Syringocystadenocarcinoma papilliferum (SCACP) is a rare malignant adnexal neoplasm, which is considered as a malignant counterpart of syringocystadenoma papilliferum (SCAP). Clinically, SCACP appears as a nodule, inflammatory plaque, or tumor. The lesion is usually covered with crusts, which are formed by secretion of the apocrine epithelial cells. Histologically, SCACP resembles SCAP, with cystic papillomatous invaginations connected to the skin surface by funnel-shaped structures lined by infundibular epithelium. The stroma of the tumor consists of a dense inflammatory infiltrate of plasma cells and lymphocytes. SCACP differs from SCAP in terms of the architectural and cytological features of the tumor cells, and is characterized by higher nuclear cytoplasmic ratio, nuclear irregularity, coarse chromatin, and increased mitotic activity. However, the immunohistochemical findings of SCACP vary. Since only 49 cases of SCACP have been reported in the English literature, the clinical and histologic characteristics of SCACP have not been fully established. Further studies on the diagnostic criteria for SCACP are warranted. Here, we report a rare case of SCACP and present a review of other relevant literature.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Células Plasmáticas
/
Piel
/
Neoplasias de las Glándulas Sudoríparas
/
Cromatina
/
Linfocitos
/
Citoplasma
/
Células Epiteliales
/
Epitelio
Idioma:
Inglés
Revista:
Annals of Dermatology
Año:
2019
Tipo del documento:
Artículo
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