Association between shift work and hyperhomocysteinemia in male workers
Annals of Occupational and Environmental Medicine
;
: e1-2019.
Artículo
en Inglés
| WPRIM
| ID: wpr-762585
ABSTRACT
BACKGROUND:
Shift work is associated with a higher risk of cardiovascular diseases. Here, we sought to assess the relationship between shift work and plasma homocysteine levels. Determining the correlations between shift work and homocysteine levels may provide a better understanding of the mechanisms underlying cardiovascular diseases.METHODS:
This study was performed using data from routine health examinations of steel workers in 2017. In total, 431 male workers (70 daytime workers and 361 shift workers) employed on a rolling departure schedule were recruited. Plasma homocysteine levels > 15 μmol/L were considered elevated. The χ2, analysis of variance, and multiple logistic regression analyses were used to examine the association between shift work and plasma homocysteine levels.RESULTS:
In comparison to daytime workers, the odds ratio (OR) of hyperhomocysteinemia in individuals with < 10 years of shift work was 1.14 (95% confidence interval [CI] 0.64–2.03), compared to 2.01 (95% CI 1.14–3.54) for workers with ≥ 10 years of experience. After adjusting for confounding variables, the adjusted OR for shift workers with < 10 years of experience was 0.95 (95% CI 0.50–1.80), compared to 2.00 (95% CI 1.07–3.74) for workers with ≥ 10 years of experience.CONCLUSIONS:
The risk of hyperhomocysteinemia was significantly higher in shift workers compared to those working normal daytime hours, particularly among long-term shift workers.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Citas y Horarios
/
Plasma
/
Acero
/
Enfermedades Cardiovasculares
/
Modelos Logísticos
/
Oportunidad Relativa
/
Hiperhomocisteinemia
/
Homocisteína
Tipo de estudio:
Estudio de etiología
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Annals of Occupational and Environmental Medicine
Año:
2019
Tipo del documento:
Artículo
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