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Comparing adult height gain and menarcheal age between girls with central precocious puberty treated with gonadotropin-releasing hormone agonist alone and those treated with combined growth hormone therapy
Annals of Pediatric Endocrinology & Metabolism ; : 116-123, 2019.
Artículo en Inglés | WPRIM | ID: wpr-762602
ABSTRACT

PURPOSE:

This study aimed to investigate the outcomes of gonadotropin-releasing hormone agonist (GnRHa) therapy with or without growth hormone (GH) therapy for girls with idiopathic central precocious puberty (CPP).

METHODS:

The medical records of 166 girls diagnosed with CPP from 2002 to 2017 were retrospectively reviewed. All included patients were treated with GnRHa for ≥36 months. Changes in height standard deviation score (SDS) for bone age, chronological age (CA), and predicted adult height (PAH) were assessed for the first three years of treatment. The final height gain SDS was calculated as the difference between the initial PAH SDS and adult height (AH) SDS; these were then compared between the GnRHa group (group A, n=135) and the combined GnRHa/GH group (group B, n=31).
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Pubertad Precoz / Estatura / Hormona del Crecimiento / Registros Médicos / Estudios Retrospectivos / Hormona Liberadora de Gonadotropina / Pubertad Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Adolescente / Adulto / Femenino / Humanos Idioma: Inglés Revista: Annals of Pediatric Endocrinology & Metabolism Año: 2019 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Pubertad Precoz / Estatura / Hormona del Crecimiento / Registros Médicos / Estudios Retrospectivos / Hormona Liberadora de Gonadotropina / Pubertad Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Adolescente / Adulto / Femenino / Humanos Idioma: Inglés Revista: Annals of Pediatric Endocrinology & Metabolism Año: 2019 Tipo del documento: Artículo