Association of metformin and statin medications with surrogate measures of cardiovascular disease in youth with type 1 diabetes: the SEARCH for diabetes in youth study
Annals of Pediatric Endocrinology & Metabolism
;
: 187-194, 2019.
Artículo
en Inglés
| WPRIM
| ID: wpr-762613
ABSTRACT
PURPOSE:
Youth with type 1 diabetes mellitus (T1DM) are at risk of cardiovascular disease (CVD). We evaluated if metformin or statin use was associated with surrogate measures of improved CVD.METHODS:
We included participants from the SEARCH observational study. Participants treated with insulin plus metformin (n=42) or insulin plus statin (n=39) were matched with 84 and 78 participants, respectively, treated with insulin alone. Measures of arterial stiffness obtained were pulse wave velocity (PWV), augmentation index (AI75), and heart rate variability as standard deviation of the normal-to-normal interval (SDNN) and root mean square differences of successive NN intervals (RMSSD).
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Enfermedades Cardiovasculares
/
Estudios Prospectivos
/
Inhibidores de Hidroximetilglutaril-CoA Reductasas
/
Morinda
/
Diabetes Mellitus Tipo 1
/
Rigidez Vascular
/
Análisis de la Onda del Pulso
/
Estudio Observacional
/
Frecuencia Cardíaca
/
Insulina
Tipo de estudio:
Estudio observacional
Límite:
Adolescente
/
Humanos
Idioma:
Inglés
Revista:
Annals of Pediatric Endocrinology & Metabolism
Año:
2019
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS