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Radiation Therapy Outcome and Clinical Features of Duodenal-Type Follicular Lymphoma / Journal of the Korean Cancer Association, 대한암학회지
Cancer Research and Treatment ; : 547-555, 2019.
Artículo en Inglés | WPRIM | ID: wpr-763139
ABSTRACT

PURPOSE:

Duodenal-type follicular lymphoma (FL) is a rare variant of FL. There is still no consensus on the initial treatment, and clinical features including endoscopic findings are not familiar to most physicians. The objective of this study was to evaluate the outcome of patients who were initially treated with radiation therapy for duodenal-type FL. MATERIALS AND

METHODS:

We retrospectively analyzed 20 patients who were consecutively diagnosed with duodenal-type FL between 2008 and 2017. All patients received radiation therapywith curative intent.

RESULTS:

The median age of the patients was 52 years (range, 26 to 66 years), and females were predominant. Most patients (n=18, 90%) had stage I disease, and were diagnosed by a regular health examination in an asymptomatic state. The histological grade was one in 19 patients (95%), and the endoscopic findings were diffuse nodular (n=8), whitish granular (n=8), and mixed pattern (n=4). Radiation therapy was delivered to 17 patients with 24 Gy in 12 fractions, and to three patients with 30.6-36 Gy in 18 fractions. All patients were evaluated with endoscopy for response to radiation therapy, and complete response was achieved in 19 patients (95%). At the time of analysis, all patients survived without any evidence of late toxicities related with radiation therapy.

CONCLUSION:

Taken together, radiation therapy alone could be effective in controlling duodenal lesion. A further study with longer follow-up duration is warranted to confirm our findings.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Estudios Retrospectivos / Estudios de Seguimiento / Linfoma Folicular / Consenso / Duodeno / Endoscopía / Enfermedades Asintomáticas Tipo de estudio: Guía de Práctica Clínica / Estudio observacional / Estudio pronóstico / Factores de riesgo Límite: Femenino / Humanos Idioma: Inglés Revista: Cancer Research and Treatment Año: 2019 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Estudios Retrospectivos / Estudios de Seguimiento / Linfoma Folicular / Consenso / Duodeno / Endoscopía / Enfermedades Asintomáticas Tipo de estudio: Guía de Práctica Clínica / Estudio observacional / Estudio pronóstico / Factores de riesgo Límite: Femenino / Humanos Idioma: Inglés Revista: Cancer Research and Treatment Año: 2019 Tipo del documento: Artículo