The Association between Z-Score of Log-Transformed A Body Shape Index and Cardiovascular Disease in Korea
Diabetes & Metabolism Journal
;
: 675-682, 2019.
Artículo
en Inglés
| WPRIM
| ID: wpr-763679
ABSTRACT
BACKGROUND:
In order to overcome the limitations of body mass index (BMI) and waist circumference (WC), the z-score of the log-transformed A Body Shape Index (LBSIZ) has recently been introduced. In this study, we analyzed the relationship between the LBSIZ and cardiovascular disease (CVD) in a Korean representative sample.METHODS:
Data were collected from the Korea National Health and Nutrition Examination VI to V. The association between CVD and obesity indices was analyzed using a receiver operating characteristic curve. The cut-off value for the LBSIZ was estimated using the Youden index, and the odds ratio (OR) for CVD was determined via multivariate logistic regression analysis. ORs according to the LBSIZ value were analyzed using restricted cubic spline regression plots.RESULTS:
A total of 31,227 Korean healthy adults were analyzed. Area under the curve (AUC) of LBSIZ against CVD was 0.686 (95% confidence interval [CI], 0.671 to 0.702), which was significantly higher than the AUC of BMI (0.583; 95% CI, 0.567 to 0.599) or WC (0.646; 95% CI, 0.631 to 0.661) (P<0.001). Similar results were observed for stroke and coronary artery diseases. The cut-off value for the LBSIZ was 0.35 (sensitivity, 64.5%; specificity, 64%; OR, 1.29, 95% CI, 1.12 to 1.49). Under restricted cubic spline regression, LBSIZ demonstrated that OR started to increase past the median value.CONCLUSION:
The findings of this study suggest that the LBSIZ might be more strongly associated with CVD risks compared to BMI or WC. These outcomes would be helpful for CVD risk assessment in clinical settings, especially the cut-off value of the LBSIZ suggested in this study.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Composición Corporal
/
Enfermedad de la Arteria Coronaria
/
Enfermedades Cardiovasculares
/
Índice de Masa Corporal
/
Modelos Logísticos
/
Oportunidad Relativa
/
Curva ROC
/
Sensibilidad y Especificidad
/
Medición de Riesgo
/
Área Bajo la Curva
Tipo de estudio:
Estudio diagnóstico
/
Estudio de etiología
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adulto
/
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Diabetes & Metabolism Journal
Año:
2019
Tipo del documento:
Artículo
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