IgG4-Related Sclerosing Cholangitis and Primary Sclerosing Cholangitis
Gut and Liver
;
: 300-307, 2019.
Artículo
en Inglés
| WPRIM
| ID: wpr-763849
ABSTRACT
Sclerosing cholangitis (SC) is defined as a condition with progressive stenosis and destruction of the bile ducts due to diffuse inflammation and fibrosis and currently includes three categories primary sclerosing cholangitis (PSC), secondary cholangitis, and IgG4-related sclerosing cholangitis (IgG4-SC). SC categories share similar clinical features, such as cholestasis. Patients with SC present with cholestatic symptoms, including jaundice and pruritus, and blood tests reveal elevation of cholestatic enzymes. Cholangiography, endoscopic or magnetic, is inevitably required for making a diagnosis. Although the presentation of IgG4-SC and PSC are similar, the comorbidities, treatment response, and outcomes differ significantly, and therefore, it is strongly advisable to be familiar with these two diseases to make a correct diagnosis. Differentiation of cholangiocarcinoma from IgG4-SC and PSC is also extremely important. In this review, the clinical characteristics, comorbidities, treatment and outcomes of IgG4-SC and PSC will be outlined based on experience mainly from Japan.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Prurito
/
Conductos Biliares
/
Fibrosis
/
Inmunoglobulina G
/
Colangiografía
/
Colangitis Esclerosante
/
Comorbilidad
/
Colangitis
/
Colestasis
/
Colangiocarcinoma
Tipo de estudio:
Estudio diagnóstico
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Gut and Liver
Año:
2019
Tipo del documento:
Artículo
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