Conservative hysteroscopic treatment of stage I well differentiated endometrial cancer in patients with high surgical risk: a pilot study / 부인종양
Journal of Gynecologic Oncology
;
: e62-2019.
Artículo
en Inglés
| WPRIM
| ID: wpr-764521
ABSTRACT
OBJECTIVE:
To report hysteroscopic treatment combined with levonorgestrel-releasing intrauterine device (LNG-IUD) to treat women with early well differentiated endometrial cancer (EC) at high surgical risk.METHODS:
Nine women diagnosed with stage IA, grade 1 endometrioid EC which was contraindicated or refused standard treatment with external beam radiation therapy with or without brachytherapy were enrolled in our prospective study. Endo-myometrial hysteroscopic resection of the whole uterine cavity and the placement of LNG-IUD for 5 years was performed. Response rate, perioperative complications, and recurrence of disease were evaluated.RESULTS:
None had intra or post-operative complications and all were discharged no later than the third day of hospitalization. After 6 months from surgery, all the women showed a complete regression of the lesion. All the women completed the 5 years follow-up and in no case was detected sign of recurrence. Two women died for causes unrelated to the tumor or the ongoing therapy.CONCLUSION:
The alternative treatment with endo-myometrial hysteroscopic resection and LNG-IUD in women with stage IA, grade 1 endometrioid EC showed initial encouraging outcomes in terms of effectiveness and safety.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Recurrencia
/
Braquiterapia
/
Histeroscopía
/
Proyectos Piloto
/
Estudios Prospectivos
/
Estudios de Seguimiento
/
Neoplasias Endometriales
/
Hospitalización
/
Dispositivos Intrauterinos
/
Obesidad
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Journal of Gynecologic Oncology
Año:
2019
Tipo del documento:
Artículo
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