Frozen Cytology of Meningeal Malignant Solitary Fibrous Tumor/Hemangiopericytoma
Journal of Pathology and Translational Medicine
;
: 192-197, 2019.
Artículo
en Inglés
| WPRIM
| ID: wpr-766016
ABSTRACT
A 51-year-old woman presented with severe dizziness. The brain magnetic resonance image revealed a 5.5 cm multiloculated mass with a thick rim in the left temporal lobe. Cytological examination of frozen diagnosis of the mass showed hypercellular sheets of round and rhabdoid cells in a hemorrhagic background, and two mitotic figures were observed. Histologically, the excised dura-based mass consisted of predominantly round cells with small foci of rhabdoid tumor cells in a pseudoalveolar pattern in a hemorrhagic background, and the cells showed nuclear positivity for signal transducer and activator of transcription 6 as well as frequent mitosis. The mass was diagnosed as a grade 3 solitary fibrous tumor (SFT)/hemangiopericytoma (HPC). The cytological diagnosis of SFT/HPC is challenging because of the heterogeneous cytological findings, such as histological heterogeneity, and because there are no standardized cytological criteria for malignant SFT/HPC. Cytological findings, such as singly scattered small cells, hypercellularity, rare ropy collagen, and round and rhabdoid cells with pseudoalveolar pattern, may assist in the diagnosis of malignant SFT/HPC.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Lóbulo Temporal
/
Características de la Población
/
Encéfalo
/
Sistema Nervioso Central
/
Colágeno
/
Tumor Rabdoide
/
Diagnóstico
/
Mareo
/
Factor de Transcripción STAT6
/
Tumores Fibrosos Solitarios
Tipo de estudio:
Estudio diagnóstico
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Journal of Pathology and Translational Medicine
Año:
2019
Tipo del documento:
Artículo
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