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CircRNA as a new field in human disease research / 中国中药杂志
China Journal of Chinese Materia Medica ; (24): 457-462, 2018.
Artículo en Chino | WPRIM | ID: wpr-771715
ABSTRACT
For the characteristics of high stability, high conservation between species, and tissue specificitycircular RNA(circRNA) has been expected to become a new molecular biomarker for the clinical diagnosistreatment and prognosis, and the potential target for targeted therapy. Study on the traditional Chinese medicine(TCM) syndrome includes not only the macro indexes collected by using four traditional methods of diagnosis, but also contains some micro information that can not be achieved by using the four traditional diagnosis methods. The questions such as how to deal with the relationship between the holistic concept of TCM and micro research, and how to solve the contradiction between the fuzziness of syndrome description and the accuracy of microscopic research, need to be considered before the micro research in TCM syndrome. circRNA as a new field of understanding human disease, may provide some ideas for the TCM syndrome research due to its characteristics. Overall, it is necessary to pay attention to explore the molecular level with same syndrome in different diseases and reveal the connotation and essence of syndromes by understanding of circRNA.
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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Síndrome / ARN / Biomarcadores / Investigación Biomédica / Genética / Medicina Tradicional China Tipo de estudio: Estudio diagnóstico / Estudio pronóstico Límite: Humanos Idioma: Chino Revista: China Journal of Chinese Materia Medica Año: 2018 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Síndrome / ARN / Biomarcadores / Investigación Biomédica / Genética / Medicina Tradicional China Tipo de estudio: Estudio diagnóstico / Estudio pronóstico Límite: Humanos Idioma: Chino Revista: China Journal of Chinese Materia Medica Año: 2018 Tipo del documento: Artículo