Application of metabolic network model to analyze intracellular metabolism of industrial microorganisms / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 1901-1913, 2019.
Artículo
en Chino
| WPRIM
| ID: wpr-771744
ABSTRACT
To quickly and efficiently understand the intracellular metabolic characteristics of industrial microorganisms, and to find potential metabolic engineering targets, genome-scale metabolic network models (GSMMs) as a systems biology tool, are attracting more and more attention. We review here the 20-year history of metabolic network model, analyze the research status and development of GSMMs, summarize the methods for model construction and analysis, and emphasize the applications of metabolic network model for analyzing intracellular metabolic activity of microorganisms from cellular phenotypes, and metabolic engineering. Furthermore, we indicate future development trend of metabolic network model.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Microbiología Industrial
/
Biología de Sistemas
/
Redes y Vías Metabólicas
/
Ingeniería Metabólica
/
Genética
/
Modelos Biológicos
Tipo de estudio:
Estudio pronóstico
Idioma:
Chino
Revista:
Chinese Journal of Biotechnology
Año:
2019
Tipo del documento:
Artículo
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