Oral microbiological diversity in patients with salivary adenoid cystic carcinoma / 华西口腔医学杂志
West China Journal of Stomatology
;
(6): 304-308, 2019.
Artículo
en Chino
| WPRIM
| ID: wpr-772656
ABSTRACT
OBJECTIVE@#The aim of this study was to identify the differences in microbial diversity and community in patients with salivary adenoid cystic carcinoma (SACC).@*METHODS@#Saliva was collected from 13 patients with SACC confirmed by histopathological diagnosis and 10 healthy control subjects. Total metagenomic DNA was extracted. The DNA amplicons of the V3-V4 hypervariable regions of the 16S rRNA gene were generated and subjected to high-throughput sequencing. Microbial diversity and community structure were analyzed with Mothur software.@*RESULTS@#A total of 16 genera of dominant bacteria in the SACC group were found, including Streptococcus (36.68%), Neisseria (8.55%), Prevotella_7 (7.53%), and Veillonella (6.37%), whereas 15 dominant bacteria in the control group were found, including Streptococcus (18.41%), Neisseria (18.20%), Prevotella_7 (8.89%), Porphyromonas (6.20%), Fusobacterium (5.86%) and Veillonella (5.82%). The statistically different phyla between the two groups were Firmicutes, Proteobacteria and Fusobacterium (P<0.05). The statistically different genera between the two groups were Streptococcus, Neisseria and Porphyromonas (P<0.05), and Capnocytophaga was only detected in patients with SACC.@*CONCLUSIONS@#Significant differences were observed in the oral microorganisms between the two groups.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Saliva
/
Bacterias
/
Neoplasias de las Glándulas Salivales
/
ARN Ribosómico 16S
/
Porphyromonas
/
Carcinoma Adenoide Quístico
/
Microbiología
Límite:
Humanos
Idioma:
Chino
Revista:
West China Journal of Stomatology
Año:
2019
Tipo del documento:
Artículo
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