Study advances in regulation effect of Tripterygium wilfordii and its extracts on innate immune system in rheumatoid arthritis cases / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3384-3390, 2019.
Artículo
en Chino
| WPRIM
| ID: wpr-773706
ABSTRACT
Rheumatoid arthritis( RA) is an autoimmune disease characterized by chronic and aggressive polyarthritis. The innate immunity mechanism plays a key role in the pathogenesis of RA. Tripterygium wilfordii and its extracts have regulatory effects on innate immune cells including macrophages,dendritic cells,neutrophils,mast cells,NK cells,NKT cells,etc.,as well as a variety of innate immune molecules including cytokines,adhesion molecules,patterns recognition receptor( PRR) and the complement molecules,showing a regulatory effect in the pathogenesis of RA innate immunity. In this paper,the recent domestic and foreign researches on the pathogenesis of RA with innate immunity involved were reviewed and the research status of T. wilfordii and its extracts on the regulation of innate immunity involved in RA was summarized.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Artritis Reumatoide
/
Medicamentos Herbarios Chinos
/
Extractos Vegetales
/
Química
/
Tripterygium
/
Usos Terapéuticos
/
Quimioterapia
/
Inmunidad Innata
Límite:
Humanos
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2019
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS