CRISPR/Cas9 System and Its Advances in Gene Therapy of Hematologic Diseases--Review / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 1863-1867, 2018.
Article
en Zh
| WPRIM
| ID: wpr-774371
Biblioteca responsable:
WPRO
ABSTRACT
In recent years, with the development of gene editing technology, the site-specific genome can be modified. The curability of genetic disease may be achieved by the use of gene editing techniques. As the simplicity, high specificity and economical efficiency, much attention has been paid to the CRISPR/Cas9 system, which was been widely used in research of molecular biology and other fields of life science. In this review, the mechanism for CR1SPR/Cas9 system and the progress of gene therapy, such as for hemophilia, betathalassaemia and chronic myeloid leukemia were summarized briefly.
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Terapéutica
/
Terapia Genética
/
Sistemas CRISPR-Cas
/
Edición Génica
/
Enfermedades Hematológicas
/
Biología Molecular
Límite:
Humans
Idioma:
Zh
Revista:
Journal of Experimental Hematology
Año:
2018
Tipo del documento:
Article