Research advances on the role of exosomes in chemotherapy resistance of ovarian cancer / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 116-120, 2019.
Artículo
en Chino
| WPRIM
| ID: wpr-775246
ABSTRACT
Chemotherapy resistance is one of the biggest challenges in treatment of ovarian cancer. Mounting evidence shows that the exosomes shedding from tumor cells are considered to be involved in chemotherapy resistance of ovarian cancer by enhanced exosomal export of drugs, transferring RNAs or proteins and interfering with the bioactivity of therapeutic anti-tumor antibodies. In this review, we display the correlation between exosomes and chemotherapy resistance of ovarian cancer, the mechanism of exosomes involved in chemotherapy resistance of ovarian cancer, and discuss the potential clinical values of exosomes in chemotherapy resistance of ovarian cancer.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Neoplasias Ováricas
/
Resistencia a Antineoplásicos
/
Usos Terapéuticos
/
Quimioterapia
/
Exosomas
/
Carcinoma Epitelial de Ovario
/
Metabolismo
/
Antineoplásicos
Límite:
Femenino
/
Humanos
Idioma:
Chino
Revista:
Journal of Zhejiang University. Medical sciences
Año:
2019
Tipo del documento:
Artículo
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