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Effect of long-term intake of ginseng extracts on gut microbiota in rats / 中国中药杂志
China Journal of Chinese Materia Medica ; (24): 3927-3932, 2018.
Artículo en Chino | WPRIM | ID: wpr-775395
ABSTRACT
As a traditional Chinese medicine in China, ginseng has a wide range of medicinal and health value. At present, the nutritional value of ginseng as a medicinal food has been a hotspot in studies. Intestinal flora plays an important role in the organism, which has been confirmed by many researchers. In order to find out the effect of long-term intake of ginseng extracts on the gut microbiota structure of rats, MiSeq sequencing platform was applied in macro gene sequencing of cecal contents in the long-term use of ginseng extracts modelin rats. According to the findings, after long-term administration with ginseng extracts, probiotics such as Bifidobacterium, Lactobacillus, Allobaculum and Clostridium, in the intestinal flora of rats were significantly increased, suggesting that long-term intake of ginseng extracts could facilitate the growth of probiotics. Meanwhile, some pathogenic bacteria, such as Butyricimonas, Parabacteroides, Alistipes, Helicobacter, were significantly down-regulated, indicating that long-term intake of ginseng extracts may have a positive effect in inhibiting the colonization of pathogenic bacteria. In conclusion, this study provided an important basis for the research on the effect of long-term use of ginseng extracts on the intestinal flora of rats.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Farmacología / Bacterias / Extractos Vegetales / Química / China / Clasificación / Microbioma Gastrointestinal / Panax Tipo de estudio: Estudio pronóstico Límite: Animales País/Región como asunto: Asia Idioma: Chino Revista: China Journal of Chinese Materia Medica Año: 2018 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Farmacología / Bacterias / Extractos Vegetales / Química / China / Clasificación / Microbioma Gastrointestinal / Panax Tipo de estudio: Estudio pronóstico Límite: Animales País/Región como asunto: Asia Idioma: Chino Revista: China Journal of Chinese Materia Medica Año: 2018 Tipo del documento: Artículo