Clinical Research on Alzheimer's Disease: Progress and Perspectives / 神经科学通报·英文版
Neuroscience Bulletin
;
(6): 1111-1118, 2018.
Artículo
en Inglés
| WPRIM
| ID: wpr-775511
ABSTRACT
Alzheimer's disease (AD), the most common type of dementia, is becoming a major challenge for global health and social care. However, the current understanding of AD pathogenesis is limited, and no early diagnosis and disease-modifying therapy are currently available. During the past year, significant progress has been made in clinical research on the diagnosis, prevention, and treatment of AD. In this review, we summarize the latest achievements, including diagnostic biomarkers, polygenic hazard score, amyloid and tau PET imaging, clinical trials targeting amyloid-beta (Aβ), tau, and neurotransmitters, early intervention, and primary prevention and systemic intervention approaches, and provide novel perspectives for further efforts to understand and cure the disease.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Terapéutica
/
Sangre
/
Imagen por Resonancia Magnética
/
Biomarcadores
/
Progresión de la Enfermedad
/
Investigación Biomédica
/
Diagnóstico
/
Enfermedad de Alzheimer
/
Métodos
Tipo de estudio:
Estudio diagnóstico
/
Estudio de tamizaje
Límite:
Animales
/
Humanos
Idioma:
Inglés
Revista:
Neuroscience Bulletin
Año:
2018
Tipo del documento:
Artículo
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