Advances in the Diagnosis and Therapy of Double-hit Lymphoma--Review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1311-1315, 2019.
Artículo
en Chino
| WPRIM
| ID: wpr-775723
ABSTRACT
Abstract Double-hit lymphoma (DHL) is a high-grade B-cell lymphoma with MYC and BCL-2/BCL-6 rearrangement, which is a invasive disease with a poor prognosis. FISH is the most important diagnostic method. There is no standard protocol for this disease yet. New therapeutic approaches including targeted therapy,checkpoint inhibitors and chimeric antigen receptor T-cell therapy are changing the paradigm of treatment for DHL. This review summarizes new developments in diagnosis and treatment of double-hit lymphoma.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Inmunoterapia Adoptiva
/
Linfoma de Células B
/
Proteínas Proto-Oncogénicas c-myc
/
Proteínas Proto-Oncogénicas c-bcl-2
/
Predisposición Genética a la Enfermedad
/
Proteínas Proto-Oncogénicas c-bcl-6
Tipo de estudio:
Estudio diagnóstico
/
Guía de Práctica Clínica
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Experimental Hematology
Año:
2019
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS