Values of Longitudinal and Transverse Plane Ratios in Predicting the Risk of Malignant Thyroid Nodules / 中国医学科学院学报

ABSTRACT

Objective To compare the predictive value of different ratio measurement in predicting the risk of malignant thyroid nodules and to determine the best value of ratio in diagnosing thyroid nodules.Methods The clinical data of 342 thyroid nodules diagnosed by ultrasonography and confirmed by histology in our hospital from January 2018 to August 2018 were analyzed.The ratio of nodules in different sections,including longitudinal plane ratio(A/T)and transverse plane ratio(A/T),was obtained through the maximum head-foot diameter(T),the maximum left-right diameter(T),and the anterior-posterior diameter(A)of transverse section measured by ultrasonography.The correlation of histological diagnosis of benign or malignant nodule with longitudinal ratio and transverse ratio were analyzed.Results The A/T and A/T of malignant nodules were 1.00(0.83,1.17)and 0.81(0.65,1.00),respectively,which were significantly higher than those of benign nodules [0.81(0.67,0.93)(=-6.567,=0.000)and 0.63(0.52,0.75)(=-7.239,=0.000)].The area under the ROC curve of A/T and A/T was 0.734 and 0.712,respectively,showing no significant difference(area difference0.0210,standard error0.0213,95%-0.0207-0.0627,=0.987,=0.3235).The threshold values of A/T and A/T for predicting malignant nodules were 0.784 161 5 and 0.985 714 5,respectively.Conclusions Both A/T and A/T has similar diagnostic value in predicting the risk of malignant nodules.The best cutoff value of the above two ratios are 0.78 and 0.99 respectively.