Progress on the Study of Targeting FGFR in Squamous Non-small Cell Lung Cancer / 中国肺癌杂志
Chinese Journal of Lung Cancer
;
(12): 116-120, 2018.
Artículo
en Chino
| WPRIM
| ID: wpr-776369
ABSTRACT
Squamous cell lung cancer (SqCLC) is a unique clinical and histologic category of non-small cell lung cancer (NSCLC). Most of patients with SqCLC tend to be older, typically at advanced stage, associated with smoking and have more complications. With progress of targeted therapy of lung cancer, we identified several potential actionable genetic abnormalities such as FGFR. Several FGFR inhibitors have been approved for clinical use in different cancers. And some of these agents are currently under investigation in clinical trials for SqCLC. This article summarizes the current knowledge about FGFR aberrations, the relative inhibitors in development and clinical data in SqCLC.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Carcinoma de Células Escamosas
/
Receptores de Factores de Crecimiento de Fibroblastos
/
Carcinoma de Pulmón de Células no Pequeñas
/
Quimioterapia
/
Terapia Molecular Dirigida
/
Genética
/
Neoplasias Pulmonares
/
Metabolismo
/
Métodos
/
Mutación
Tipo de estudio:
Estudio pronóstico
Límite:
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Lung Cancer
Año:
2018
Tipo del documento:
Artículo
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