Chemical constituents from ethyl acetate-soluble extraction of Valeriana jatamansi / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 100-108, 2018.
Artículo
en Chino
| WPRIM
| ID: wpr-776417
ABSTRACT
Application of a combination of various chromatographic techniques including column chromatography over silica gel, Sephadex LH-20, macroporous adsorbent resin, and reversed-phase HPLC, led to the isolation of 173 compounds including irdidoids, monoterpenes, sesquiterpenes, triterpenes, lignans, flavonoids, and simple aromatic derivatives from the ethyl acetate-soluble fraction of the whole plants of Valeriana jatamansi(Valerianaceae), and their structures were elucidated by spectroscopic methods including 1D, 2D NMR UV, IR, and MS techniques. Among them, 77 compounds were new. In previous reports, we have described the isolation, structure elucidation, and bioactivities of 68 new and 25 known compounds. As a consequence, we herein reported the isolation and structure elucidation of the remaining 9 new and 71 known compounds, the structure revision of valeriotriate A(8a), as well as cytotoxicity of some compounds.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Sesquiterpenos
/
Triterpenos
/
Valeriana
/
Flavonoides
/
Extractos Vegetales
/
Estructura Molecular
/
Química
/
Cromatografía Líquida de Alta Presión
/
Lignanos
/
Monoterpenos
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2018
Tipo del documento:
Artículo
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