A Case of Malignant Leydig Cell Tumor of Testis in Adult / 대한비뇨기과학회지

ABSTRACT

Leydig cell tumors of the testis is only 1 to 3% of all testicular tumors. Although they are usually clinically benign, about 1O% of the reported cases has been associated with a malignant course. Malignant testicular leydig cell tumors occur exclusively in adult. Early metastasis is usually seen and there is no proved sensitivity to radiation or chemotherapeutic regimens in patients with disseminated tumor with poor prognosis. A-70-year-old man was admitted to Korea University Haewha Hospital with rapid growing, nontender testicular mass. On physical examination, right testicular hard mass measuring 9 x 6 x 5cm in size showed negative transilumination test. Under the impression of testicular tumor, radical orchiectomy was performed. Histologic and electron-microscopic features revealed malignant leydig cell tumor and the literatures are reviewed.