New octadecanoid derivatives from the seeds of Ipomoea nil / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 303-307, 2019.
Artículo
en Inglés
| WPRIM
| ID: wpr-776882
ABSTRACT
Four new octadecanoid derivatives (1-4) including a pair of enantiomers (1/2), along with 12 known analogues (5-16), were isolatedfrom the seeds of Ipomoea nil. Their structures were determined by detailed spectroscopic analyses and comparison with reported data of structurally related compounds, with the absolute configurations of 1 and 2 being assigned by an in situ dimolybdenum ECD method. Our bioassays revealed that these isolates did not show ABTS radical scavenging activity while 10 and 13 displayed better α-glucosidase inhibitory activity than the positive control acarbose (IC 167.7 ± 1.55 μmol·L), with IC of 92.73 ± 3.12 and 11.39 ± 2.18μmol·L, respectively.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Semillas
/
Extractos Vegetales
/
Estructura Molecular
/
Química
/
Concentración 50 Inhibidora
/
Ipomoea nil
/
Ácidos Grasos
/
Inhibidores de Glicósido Hidrolasas
/
Metabolismo
Idioma:
Inglés
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Año:
2019
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS