Eight new cytotoxic annonaceous acetogenins from the seeds of Annona squamosa / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 291-297, 2019.
Artículo
en Inglés
| WPRIM
| ID: wpr-776884
ABSTRACT
Eight new annonaceous acetogenins, squamotin A-D (1-4), annosquatin IV-V (5 and 6), muricin O (7) and squamosten B (8), together with four known ones (9-12) were isolated from the seeds of Annona squamosa. Their structures were elucidated by chemical methods and spectral data. The inhibitory activities of compound 1-9 against three multidrug resistance cell lines were evaluated. All tested compounds showed strong cytotoxicity.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacología
/
Semillas
/
Ensayos de Selección de Medicamentos Antitumorales
/
Extractos Vegetales
/
Estructura Molecular
/
Supervivencia Celular
/
Química
/
Resistencia a Antineoplásicos
/
Annona
/
Línea Celular Tumoral
Límite:
Humanos
Idioma:
Inglés
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Año:
2019
Tipo del documento:
Artículo
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