Two new nimbolinin- and trichilin-class limonoids isolated from the fruits of Melia azedarach / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 227-230, 2019.
Artículo
en Inglés
| WPRIM
| ID: wpr-776890
ABSTRACT
Two new furan fragment isomerized limonoids, meliazedalides A and B (compounds 1 and 2), were isolated from the fruits of Melia azedarach Linn.. Their chemical structures were elucidated on the basis of HR-ESI-MS and 1D and 2D NMR data, which belonged to nimbolinin- and trichilin-class, respectively. Compound 2 exhibited weak inhibitory effect on NO production in lipopolysaccharide (LPS)-activated RAW 264.7 macrophages with IC being 37.41 μmol·L.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacología
/
Medicamentos Herbarios Chinos
/
Estructura Molecular
/
Química
/
Melia azedarach
/
Limoninas
/
Frutas
/
Macrófagos
/
Metabolismo
/
Antiinflamatorios
Límite:
Animales
Idioma:
Inglés
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Año:
2019
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS