Study progress of the correlation between peri-implantitis, IL-1β, TNF-α and NF-κB signal transduction / 口腔疾病防治
Journal of Prevention and Treatment for Stomatological Diseases
;
(12): 673-676, 2018.
Artículo
en Chino
| WPRIM
| ID: wpr-777716
ABSTRACT
@#Increasing numbers of edentulous patients and patients with dental defects are willing to accept implant restorations. However, the development of peri-implantitis is a major factor leading to implant failure. The worsening of peri-implantitis promotes the secretion of inflammatory cytokines such as IL-1β and TNF-α and the gene expression of RANKL, inhibits the gene expression of OPG, and increases osteoclast activity, which promotes bone absorption indirectly and leads to a negative balance in bone metabolism. To gain knowledge about the relationship between peri-implantitis and NF-κB signaling pathways, this article summarizes related reports about peri-implantitis and NF-κB signaling pathways, explores the regulatory mechanism by which peri-implantitis affects bone metabolism and NF-κB signaling, discusses the effect of immunological cytokines on NF-κB signaling pathways when inflammation arises, and provides a theoretical foundation for peri-implantitis research and prevention.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Prevention and Treatment for Stomatological Diseases
Año:
2018
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS