Diastolic Function in Patients with Hypertrophic Cardiomyopathy: Evaluation Using the Phase-contrast MRI Measurement of Mitral Valve and Pulmonary Vein Flow Velocities
Journal of the Korean Society of Magnetic Resonance in Medicine
;
: 314-322, 2014.
Artículo
en Inglés
| WPRIM
| ID: wpr-77849
ABSTRACT
PURPOSE:
Diastolic dysfunction is a common problem in patients with hypertrophic cardiomyopathy (HCM). The purpose of this study was to assess the role of MRI in the assessment of diastolic function using mitral valve and pulmonary vein flow velocities in HCM patients. METHODS ANDRESULTS:
Phase-contrast MRI (mitral valve and pulmonary vein) and transthoracic echocardiography was successfully performed for 59 HCM patients (44 men and 15 women; mean age, 51 years). Forty-nine patients had a diastolic dysfunction; grade 1 (n = 20), grade 2 (n = 27), and grade 3 (n = 2) using echocardiography, and ten patients had normal diastolic function. The transmitral inflow parameters (E, A, and E/A ratios) obtained by MRI showed positive correlation with the same parameters measured by echocardiography (Pearson's r values were 0.47, 0.60, and 0.75 for E, A, E/A, respectively, all P < 0.001). With the flow information of the pulmonary vein from cardiac MRI, pseudo-normalized pattern (n = 8) could be distinguished from true normal filling pattern (n = 17), and the diastolic function grades by cardiac MRI showed moderate agreement with those of echocardiography (kappa value = 0.45, P < 0.001).CONCLUSIONS:
Assessment of left ventricle diastolic function is feasible using phase-contrast MRI in HCM patients. Analysis of pulmonary vein flow velocity on MRI is useful for differentiating pseudo-normal from normal diastolic function in HCM patients.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Venas Pulmonares
/
Velocidad del Flujo Sanguíneo
/
Cardiomiopatía Hipertrófica
/
Imagen por Resonancia Magnética
/
Ecocardiografía
/
Ecocardiografía Doppler
/
Diástole
/
Ventrículos Cardíacos
/
Válvula Mitral
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Journal of the Korean Society of Magnetic Resonance in Medicine
Año:
2014
Tipo del documento:
Artículo
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