Association between nonalcoholic fatty liver disease and depression / 临床肝胆病杂志

ABSTRACT

At present, nonalcoholic fatty liver disease (NAFLD) has become one of the most common chronic liver diseases in the world. With the development of the bio-psycho-social medical model, the mental health problems of patients with NAFLD are gradually attracting more and more attention. In recent years, more and more studies have been conducted on the association between NAFLD and psychiatric diseases, especially depression. Studies have shown that there is a significant correlation between NAFLD and depression; however, the common pathophysiological mechanism of such correlation is still unclear and further studies are needed to determine their causal relationship and treatment. This article reviews the research advances in the association between NAFLD and depression, common pathophysiological mechanism, and treatment, so as to lay a foundation for further research on these two disease and help with their prevention and treatment in future clinical practice.