Research Progress of m6A-Methylation in Acute Leukemia-Review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 2014-2018, 2019.
Artículo
en Chino
| WPRIM
| ID: wpr-781502
ABSTRACT
Epigenetic abnormalities play an important role in the pathogenesis of hematological malignancies, especially acute leukemia (AL). Similar to DNA methylation and histone modifications, RNA methylation is another important epigenetic modification. m6A methylation is one of the most prevalent and extensively studied RNA methylation. m6A methylation is involved in many biological and pathological process. Recent studies have found that m6A methylation is involved in the occurrence, development and drug-resistance of AL. This review focuses on the research progress of m6A methylation in AL.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Leucemia
/
Metilación de ADN
/
Epigénesis Genética
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Experimental Hematology
Año:
2019
Tipo del documento:
Artículo
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