Prenatal tobacco exposure and ADHD symptoms at pre-school age: the Hokkaido Study on Environment and Children's Health
Environmental Health and Preventive Medicine
;
: 74-74, 2019.
Artículo
en Inglés
| WPRIM
| ID: wpr-781569
ABSTRACT
BACKGROUND@#There have been inconsistent findings reported on maternal passive smoking during pregnancy and child risk of ADHD. In this study, ADHD symptoms at pre-school age children in association with prenatal passive and active tobacco smoke exposure determined by maternal plasma cotinine levels in the third trimester were investigated.@*METHODS@#This was a follow-up study of the birth cohort the Hokkaido Study on Environment and Children's Health. Children whose parents answered Strengths and Difficulties Questionnaire (SDQ) to identify child ADHD symptoms (hyperactivity/inattention and conduct problems) and total difficulties at age 5 years with available maternal plasma cotinine level at the third trimester were included (n = 3216). Cotinine levels were categorized into 4 groups; ≦ 0.21 ng/ml (non-smoker), 0.22-0.51 ng/ml (low-passive smoker), 0.52-11.48 ng/ml (high-passive smoker), and ≧ 11.49 ng/ml (active smoker).@*RESULTS@#Maternal cotinine levels of active smokers were significantly associated with an increased risk of total difficulties (OR = 1.67) and maternal low- and high-passive smoking also increased the risk (OR = 1.11, 1.25, respectively) without statistical significance. Similarly, maternal cotinine levels of active smokers were associated with an increased risk of hyperactivity/inattention (OR = 1.49). Maternal low- and high-passive smoking and active smoking increased the risk of hyperactivity/inattention (OR = 1.45, 1.43, and OR = 1.59, respectively) only in boys.@*CONCLUSION@#Our findings suggested that maternal active smoking during pregnancy may contribute to the increased risk of child total difficulties and hyperactivity/inattention at pre-school age. Pregnant women should be encouraged to quit smoking and avoid exposure to tobacco smoke.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Tercer Trimestre del Embarazo
/
Efectos Tardíos de la Exposición Prenatal
/
Psicología
/
Trastorno por Déficit de Atención con Hiperactividad
/
Sangre
/
Factores Sexuales
/
Epidemiología
/
Riesgo
/
Estudios de Seguimiento
/
Exposición Materna
Tipo de estudio:
Estudio diagnóstico
/
Estudio de etiología
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adulto
/
Child, preschool
/
Femenino
/
Humanos
/
Masculino
/
Embarazo
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Environmental Health and Preventive Medicine
Año:
2019
Tipo del documento:
Artículo
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