Gastrointestinal Stromal Tumor with Accelerated Growth Pattern in the Stomach

ABSTRACT

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract and can be benign or malignant. To date, there have been no clear standards for the preoperative assessment of GIST malignancy. Currently it is believed that tumors with diameter smaller than 2.0 cm is benign. Herein, we experienced two cases of GISTs that showed an accelerated growth pattern during the follow-up period. In both cases, the tumors were <2.0 cm in size initially and became larger unexpectedly. The resected tumors revealed GIST with intermediate risk and high risk of malignancy according to National Institutes of Health (NIH) consensus symposium.