Survival Prediction in Terminally Ill Cancer Patients: Laboratory Variables and Prospective Validation of The Palliative Prognostic Index / 대한내과학회지
Korean Journal of Medicine
;
: 359-365, 2011.
Artículo
en Coreano
| WPRIM
| ID: wpr-78410
ABSTRACT
BACKGROUND/AIMS:
The palliative prognostic index (PPI) was designed to predict life expectancy based on clinical symptoms. In this study, a PPI was constructed and used with other biological parameters to predict 3-week survival in patients with advanced cancer.METHODS:
The study included 222 patients. The PPI was constructed with five variables (performance status, oral intake, edema, dyspnea at rest, and delirium). PPI scores were grouped as follows 4 (group 1); > 4 and 6 (group 3). At admission, seven biological variables (white blood cell count, lymphocyte, C-reactive protein [CRP], bilirubin, albumin, creatinine, and lactate dehydrogenase) were measured.RESULTS:
The overall survival duration was 50 days in group 1, 22 days in group 2, and 14 days in groups 3. Using the PPI, a survival of 6 and increases in serum bilirubin and CRP levels. Furthermore, the 3-week survival rate in patients with hepatopancreatobiliary cancer was more accurately predicted using a combination of the PPI, CRP, and serum bilirubin levels.CONCLUSIONS:
Although a PPI has limitations, it can be quickly applied to determine survival duration in patients admitted to hospice and accurately predicts 3-week survival. Furthermore, bilirubin and CRP are useful factors for predicting 3-week survival in patients with gastrointestinal cancer, including hepatopancreatobiliary cancer.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Bilirrubina
/
Recuento de Células Sanguíneas
/
Proteína C-Reactiva
/
Linfocitos
/
Análisis de Supervivencia
/
Tasa de Supervivencia
/
Estudios Prospectivos
/
Esperanza de Vida
/
Sensibilidad y Especificidad
/
Cuidados Paliativos al Final de la Vida
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
/
Estudio pronóstico
Límite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Medicine
Año:
2011
Tipo del documento:
Artículo
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