The Effects of Olfactory Training with Intranasal Corticosteroid Spray in Korean Patients with Olfactory Dysfunction
Journal of Rhinology
;
: 106-112, 2019.
Artículo
en Coreano
| WPRIM
| ID: wpr-785286
ABSTRACT
OBJECTIVES: Olfactory training is an alternative treatment based on modulation of the regeneration process of the olfactory system via repeated exposure to odors. Our study aimed to investigate the impact of olfactory training with intranasal corticosteroid in Korean patients with various causes of olfactory dysfunction.SUBJECTS AND METHOD:
Our study population comprised 134 adults with olfactory dysfunction of different etiologies (postviral infection n=85; post-traumatic n=18; and idiopathic n=31). For training, patients exposed themselves to four different odors twice a day. All patients used fluticasone nasal spray (two sprays in each nostril once daily). Olfactory function was evaluated at baseline and again at three months, and results were quantified as patient TDI (threshold, discrimination, and identification) scoreRESULTS:
Olfactory function improved in 74 of 134 patients (55.2%). Etiology of olfactory disorder, sex, and age had statistically significant influence on the improvement rate of olfactory function, among which etiology of olfactory loss was the most important. However, initial severity and duration of olfactory loss had no statistically significant influence on the improvement rate. The TDI score at three months of olfactory training showed remarkable improvement, primarily because of improvements in the discrimination and identification components.CONCLUSION:
The present study showed that olfactory training with intranasal corticosteroid was beneficial to improve olfactory function in patients with olfactory dysfunction, particularly in postviral infection patients.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Regeneración
/
Discriminación en Psicología
/
Fluticasona
/
Trastornos del Olfato
/
Métodos
/
Odorantes
Tipo de estudio:
Estudio pronóstico
Límite:
Adulto
/
Humanos
Idioma:
Coreano
Revista:
Journal of Rhinology
Año:
2019
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS