The key role of mitochondrial energy metabolism disorder in the pathogenesis of depression / 药学学报
Acta Pharmaceutica Sinica
;
(12): 195-200, 2020.
Artículo
en Chino
| WPRIM
| ID: wpr-789022
ABSTRACT
Depression is a common mental illness with mood disorders as the main clinical feature. In recent years numerous studies have shown that mitochondrial function and structure are abnormal in patients with depression, and changes in mitochondrial ultrastructure can lead to energy metabolism disorders in the body. It is suggested that 'mitochondrial energy metabolism disorder' may be the pathogenesis of depression. This paper reviews the intrinsic association of mitochondrial energy metabolism with depression and notes potential mechanisms from the standpoint of mitochondrial structure and function on the molecular level. We provide a reference for understanding the pathogenesis of depression and identifying the possible targets of antidepressant drugs.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio de etiología
Idioma:
Chino
Revista:
Acta Pharmaceutica Sinica
Año:
2020
Tipo del documento:
Artículo
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