Neovascular maturity: the intervention target of vulnerable atherosclerotic plaques / 国际脑血管病杂志

ABSTRACT

Immature neovascularization in atherosclerotic plaques is closely associated with plaque vulnerability. Pathological factors with inflammation as the core in the plaques interfere with the formation of junction between endothelial cells, parietal cell coverage and basement membrane deposition, hindering the maturation of neovascularization. Improving neovascular maturity is a potential intervention target for stabilizing vulnerable atherosclerotic plaques.