Application of cell co-culture models in absorption of oral drug / 药学实践杂志
Journal of Pharmaceutical Practice
;
(6): 289-292,327, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-790469
ABSTRACT
Cell co-culture system can better simulate the inner environment of human body ,predict drug transport and metabolism in intestinal environment and increase the relation between in vitro cell model and integral animal test .In recent years ,co-culture cell model plays an increasingly important role in evaluating the absorption of oral drugs ,which becomes the highlight in the evaluation of drug oral absorption during new drug discovery .This essay summarized co-culture cell model which simulates intestinal environment and their application ,and looked into the future of their application in evaluating oral drug intestinal absorption during oral drug discovery .
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio pronóstico
Idioma:
Chino
Revista:
Journal of Pharmaceutical Practice
Año:
2015
Tipo del documento:
Artículo
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