Identification of Norvasc and counterfeit drugs based on Raman spectra of phar-maceutical excipients / 药学实践杂志
Journal of Pharmaceutical Practice
;
(6): 334-337, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-790480
ABSTRACT
Objective To build an identification method for Norvascand its counterfeit drugs based on the differences of their pharmaceutical excipients with the original and generic Amlodipine besylatetablets as tools .Methods Raman spectra of pharmaceutical excipients which were usually used in tablets were collected .Similarity algorithm and characteristic Raman bands were used to search the excipients contained in the tablets .If the excipients was not the same as excipients contained in Nor-vasc ,the tablet was judged as counterfeit drugs .Otherwise ,principal component analysis was used to identify counterfeit and generic .Results and conclusion The method based on Raman spectra of pharmaceutical excipients could identify Norvasc and counterfeit drugs efficiently and accurately .
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio diagnóstico
/
Estudio pronóstico
Idioma:
Chino
Revista:
Journal of Pharmaceutical Practice
Año:
2015
Tipo del documento:
Artículo
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