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Observation of clinical efficacy of stereotactic body radiotherapy in 28 cases of large hepatocellular carcinoma / 中华放射肿瘤学杂志
Chinese Journal of Radiation Oncology ; (6): 749-752, 2019.
Artículo en Chino | WPRIM | ID: wpr-791421
ABSTRACT
Objective To observe the survival and side effects of stereotactic body radiotherapy (SBRT) in large hepatocellular carcinoma (HCC) patients.Methods Twenty-eight large HCC patients undergoing SBRT in 302 Military Hospital from November 1,2011 to January 31,2014 were observed.The prescribed dose was 39-61 Gy/3-9f.Among them,20 patients simultaneously received transcatheter arterial embolization.The overall survival (OS),progression-free survival (PFS) and local control (LC) rates were calculated by using Kaplan-Meier method.The influencing factors of OS were analyzed by Cox regression model The influencing factors of radiation-induced liver disease (RILD) were identified by using Logistic regression analysis.Results The 1-,2-,3-and 5-year OS rates were 75%,57%,54% and 22%,respectively.The 1-,2-,3-and 5-year PFS rates were 59%,47%,36% and 18%,respectively.The 1-,2-,3-and 5-year LC rates were 92%,86%,86% and 86%,respectively.Four patients suffered from RILD and none died from RILD.Child-Pugh classification was the influencing factor of OS and RILD.Conclusion It is preliminarily believed that SBRT is an alternative and safe treatment for patients with large HCC.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Estudio pronóstico Idioma: Chino Revista: Chinese Journal of Radiation Oncology Año: 2019 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Estudio pronóstico Idioma: Chino Revista: Chinese Journal of Radiation Oncology Año: 2019 Tipo del documento: Artículo