Underlying Hemato-oncologic, Gastrointestinal-nutritional Diseases, or Prematurity May Be Risk Factors for Hypovitaminosi D in Children / 계명의대학술지
Keimyung Medical Journal
;
: 89-97, 2015.
Artículo
en Inglés
| WPRIM
| ID: wpr-79183
ABSTRACT
PURPOSE:
An adequate vitamin D level is important for normal growth, cancer prevention, controlling hormones, and immune regulation. However, no study has investigated vitamin D status in patients with serious illnesses, such as malignancies, malabsorption diseases, or prematurity in Korean children. Thus, we analyzed the results of 25-hydroxyvitamin D3 (25-D) levels in children in a single tertiary medical center.METHODS:
Children who had their vitamin D level evaluated at Keimyung University Dongsan Medical Center from January 2004 to December 2014 were included. We reviewed the medical records and laboratory test results.RESULTS:
Ninety-three children (malefemale = 4845) who had their vitamin D levels measured were included. The most common reason for measuring vitamin D level was hypocalcemia with or without neurological signs. Among the subjects, 61 children had hypovitaminosis D (25-D < 30 ng/mL). A positive correlation was detected between 25-D and total calcium levels (p = 0.001). Negative correlations were found between 25-D and immunoreactive parathyroid hormone (iPTH) levels (p = 0.002) and between 25-D and alkaline phosphatase (ALP) levels (p = 0.021). Twenty-three subjects (37.7%) had a critical underlying condition, including a hemato-oncologic issue (18.0%), gastrointestinal or nutritional problem (11.5%), and prematurity or low birth weight (8.2%).CONCLUSION:
The levels of total calcium, ALP, and iPTH were correlated with 25-D level. An underlying malignancy, malabsorption issues, or prematurity may be risk factors for hypovitaminosis D in children.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Hormona Paratiroidea
/
Vitamina D
/
Calcifediol
/
Recién Nacido de Bajo Peso
/
Registros Médicos
/
Calcio
/
Factores de Riesgo
/
Fosfatasa Alcalina
/
Hipocalcemia
Tipo de estudio:
Estudio de etiología
/
Factores de riesgo
Límite:
Niño
/
Humanos
/
Recién Nacido
Idioma:
Inglés
Revista:
Keimyung Medical Journal
Año:
2015
Tipo del documento:
Artículo
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