Clostridium difficile Infections in Children / 이화의대지
The Ewha Medical Journal
;
: 3-12, 2011.
Artículo
en Coreano
| WPRIM
| ID: wpr-7972
ABSTRACT
During the past decade, rates of Clostridium difficile infection (CDI) increased worldwide. Hypervirulent strains of C. difficile such as NAP1/BI/027 and PCR ribotype 078 have emerged that have changed the epidemiology of CDI. Especially, CDI rates also have increased in the community, in children previously thought to be at low risk. Recently, the use of gastric acid suppressant that facilitates intestinal transit of the bacteria and presence of inflammatory bowel disease has been reported as risk factors. Treatment for CDI usually relies on metronidazole or vancomycin, but recurrence rates remains high. New treatment options for multiple recurrence are challenging. In this article, we reviewed recent epidemiological changes, current knowledge of virulence factors, reasonable approach to the diagnosis, and optimal treatment of CDI. But, clinical guidelines for pediatric C. difficile disease have not been defined. It seems that the consensus and recommendations for managing pediatric CDI are urgently needed.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Recurrencia
/
Bacterias
/
Vancomicina
/
Enfermedades Inflamatorias del Intestino
/
Reacción en Cadena de la Polimerasa
/
Factores de Riesgo
/
Clostridioides difficile
/
Clostridium
/
Ribotipificación
/
Factores de Virulencia
Tipo de estudio:
Estudio de etiología
/
Guía de Práctica Clínica
/
Factores de riesgo
Límite:
Niño
/
Humanos
Idioma:
Coreano
Revista:
The Ewha Medical Journal
Año:
2011
Tipo del documento:
Artículo
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