A Case of Multifocal Papillary Thyroid Carcinoma Consisting of One Encapsulated Follicular Variant with BRAF K601E Mutation and Three Conventional Types with BRAF V600E Mutation
Korean Journal of Pathology
;
: 293-298, 2013.
Artículo
en Inglés
| WPRIM
| ID: wpr-79749
ABSTRACT
Multifocal papillary thyroid carcinoma (mPTC) comprises about 20-30% of PTC. In mPTC, individual tumor foci can be identical or frequently composed of different histological types including follicular, solid, tall-cell or conventional patterns. We report a case of mPTC consisting of one encapsulated follicular variant of papillary thyroid carcinoma (FVPTC) and three conventional PTCs in a 44-year-old woman. This case genetically demonstrates unique features including the simultaneous presence of the BRAF V600E (T1799A) mutation and the BRAF K601E (A1801G) mutation in conventional PTC and FVPTC, respectively.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Glándula Tiroides
/
Factor IX
/
Neoplasias de la Tiroides
/
Carcinoma
/
Carcinoma Papilar
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Korean Journal of Pathology
Año:
2013
Tipo del documento:
Artículo
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