Plasma Exchange in a Patient with Antineutrophil Cytoplasmic Antibody-associated Vasculitis / 대한수혈학회지
Korean Journal of Blood Transfusion
; : 254-259, 2007.
Article
en Ko
| WPRIM
| ID: wpr-80664
Biblioteca responsable:
WPRO
ABSTRACT
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a systemic autoimmune disease with a poor prognosis in untreated patients, and combination therapy with steroidsand cyclophosphamide is the current standard treatment. Treatment with immunosuppressive agents results in high remission rates; however, there is a considerable morbidity related to the immunosuppressive state, such as life-threatening infections. To reduce serious immunosuppressant-related adverse effects, potentially promising treatment options, including plasma exchange, cytapheresis, administration of intravenous immunoglobulin and TNF-alpha blocking agents have been developed. We performed plasma exchange with steroid pulse therapy for a 52 year-old female patient with pulmonary hemorrhagewith ANCA-associated crescentic glomerulonephritis. After combination therapy, the pulmonary hemorrhage and renal function recovered and myeloperoxidase (MPO)-ANCA decreased.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Plasma
/
Intercambio Plasmático
/
Pronóstico
/
Enfermedades Autoinmunes
/
Vasculitis
/
Inmunoglobulinas
/
Citaféresis
/
Factor de Necrosis Tumoral alfa
/
Peroxidasa
/
Anticuerpos Anticitoplasma de Neutrófilos
Tipo de estudio:
Prognostic_studies
Límite:
Female
/
Humans
Idioma:
Ko
Revista:
Korean Journal of Blood Transfusion
Año:
2007
Tipo del documento:
Article