Research progress in OX40/OX40L-induced transplantation tolerance / 中华微生物学和免疫学杂志
Chinese Journal of Microbiology and Immunology
;
(12): 556-558, 2018.
Artículo
en Chino
| WPRIM
| ID: wpr-806858
ABSTRACT
OX40 (CD134) is a costimulatory molecule on the surface of T cells. It binds to OX40L (CD252) that is expressed on the surface of antigen presenting cells (APC) and participates in the transmission of the second signal of T cell activation, indicating that it is of great importance to the proliferation, differentiation, survival and migration of T cells. In theory, blocking the OX40/OX40L costimulatory pathway can suppress immune response and induce immune tolerance. In this review, we reviewed the research progress in OX40/OX40L-induced transplantation tolerance.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Microbiology and Immunology
Año:
2018
Tipo del documento:
Artículo
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