Prevalence and possible causes of hypouricemia at a tertiary care hospital
The Korean Journal of Internal Medicine
; : 971-976, 2016.
Article
en En
| WPRIM
| ID: wpr-81003
Biblioteca responsable:
WPRO
ABSTRACT
BACKGROUND/AIMS: We aimed to investigate the prevalence and possible causes of hypouricemia in the Korean population and to compare our findings with published results of other populations. METHODS: We examined the serum uric acid levels of 30,757 subjects who had their uric acid values measured at least once during a 1-year period. All individuals with hypouricemia (serum uric acid < 2.0 mg/dL, n = 424) were reviewed with respect to medical drug history and concomitant diseases previously identified as being associated with hypouricemia. RESULTS: The prevalence of hypouricemia was 4.14% (299/7,223) among inpatients and 0.53% (125/23,534) among outpatients, for an overall prevalence of 1.39% (424/30,757). Possible causes associated with hypouricemia were found to be solid or hematologic malignancies (n = 86), diabetes mellitus (n = 56), and therapeutic drugs (n = 29). The medications were allopurinol (n = 11), angiotensin II receptor blockers (n = 10), salicylates (n = 6), febuxostat (n = 1), and warfarin (n = 1). In the remaining 226 individuals, the cause of hypouricemia was not identified. CONCLUSIONS: Hypouricemia is relatively common in the Korean population compared to those of other countries. The possible causes associated with hypouricemia are related to underlying diseases and medications.
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Texto completo:
1
Índice:
WPRIM
Asunto principal:
Pacientes Ambulatorios
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Ácido Úrico
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Warfarina
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Atención Terciaria de Salud
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Salicilatos
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Alopurinol
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Prevalencia
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Neoplasias Hematológicas
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Diabetes Mellitus
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Antagonistas de Receptores de Angiotensina
Tipo de estudio:
Etiology_studies
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Prevalence_studies
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Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
The Korean Journal of Internal Medicine
Año:
2016
Tipo del documento:
Article