Advances of the uricosuric drugs / 中国药科大学学报
Journal of China Pharmaceutical University
; (6): 491-496, 2016.
Article
en Zh
| WPRIM
| ID: wpr-811851
Biblioteca responsable:
WPRO
ABSTRACT
@#Promoting uric acid excretion is an important approach for the treatment of gout and hyperuricemia. There are two main approaches included in the mechanism: one is inhibiting the function of renal tubular uric acid transporter to reduce the absorption of uric acid, and promoting excretion; the other is using uricase to catalyze the oxidation of uric acid to a more water-soluble allantoin that can also increase excretion. The mechanisms and progress of the uricosuric drugs are reviewed in this paper, providing reference for the further research and development.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of China Pharmaceutical University
Año:
2016
Tipo del documento:
Article