Preparation of pumiloside and identification of its metabolites in rats by UPLC-QTOF/MS / 中国药科大学学报
Journal of China Pharmaceutical University
;
(6): 677-682, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-811990
ABSTRACT
@#In this paper, water extract of Nauclea officinalis was absorbed by AB-8 macroporous resin and subsequently gradient-eluted with alcoholic solution of different proportion to prepare pumiloside monomer of high purity. The metabolites in urine, feces and bile of rats with gavage administration were analyzed by UPLC-QTOF/MS. Accurate MS/MS data of all components were collected with full scan mode, and analyzed by MetaboLynx software. Results showed that the monomer of high-purity pumiloside was prepared and four metabolites in rats were identified.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio diagnóstico
Idioma:
Chino
Revista:
Journal of China Pharmaceutical University
Año:
2015
Tipo del documento:
Artículo
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