Two new phragmalin-type limonoids orthoesters from Entandrophragma candollei / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 680-683, 2017.
Artículo
en Inglés
| WPRIM
| ID: wpr-812068
ABSTRACT
Two new phragmalin-type limonoids orthoesters, encandollens A and B (1 and 2), were isolated from the stem barks of Entandrophragma candollei collected in Ghana. The structures of these compounds were elucidated on the basis of HR-ESI-MS, H and C NMR, HSQC, HMBC, and ROESY data. Compound 1 was a rare C-15 enolic acyl phragmalin-type limonoid orthoester. Compounds 1 and 2 exhibited weak inhibitory effects on NO production in lipopolysaccharide (LPS)-induced RAW 264.7 cells.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacología
/
Medicamentos Herbarios Chinos
/
Estructura Molecular
/
Química
/
Meliaceae
/
Corteza de la Planta
/
Limoninas
/
Macrófagos
/
Metabolismo
/
Óxido Nítrico
Límite:
Animales
Idioma:
Inglés
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Año:
2017
Tipo del documento:
Artículo
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