Megastigmane glucosides isolated from Dichrocephala benthamii / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 288-291, 2017.
Artículo
en Inglés
| WPRIM
| ID: wpr-812113
ABSTRACT
The present study was designed to investigate the chemical constituents of the whole herb of Dichrocephala benthamii. A new megastigmane glucoside (compound 1), together with its four known analogues (compounds 2-5), was obtained. Their structures were elucidated on the basis of spectroscopic analyses (UV, IR, MS, and 1D and 2D NMR). The absolute configuration of compound 1 was assigned on the basis of CD method and chemical evidence. In addition, their cytotoxicity against human hepatoma cells (HepG-2) was evaluated by the MTT method. Compound 5 showed weak activity against HepG-2, while the other compounds did not show remarkable inhibitory effects.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacología
/
Plantas Medicinales
/
Ensayos de Selección de Medicamentos Antitumorales
/
Medicamentos Herbarios Chinos
/
Estructura Molecular
/
Química
/
China
/
Asteraceae
/
Ciclohexanonas
/
Norisoprenoides
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Año:
2017
Tipo del documento:
Artículo
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